Activation of the various cyclin/cdc2 protein kinases

MJ Solomon - Current opinion in cell biology, 1993 - Elsevier
Current opinion in cell biology, 1993Elsevier
Recent research has led to the near culmination of the biochemical confirmation of the most
basic genetic predictions about how p34 cdc2 activity is controlled. The field is now moving
from a biochemical dissection of the machinery to understanding how the system is
regulated. The discovery of numerous, highly related protein kinase complexes that control
other cell cycle events will test the generality of this paradigm.
Abstract
Recent research has led to the near culmination of the biochemical confirmation of the most basic genetic predictions about how p34cdc2 activity is controlled. The field is now moving from a biochemical dissection of the machinery to understanding how the system is regulated. The discovery of numerous, highly related protein kinase complexes that control other cell cycle events will test the generality of this paradigm.
Elsevier