[CITATION][C] Identification and activation of latent transforming growth factor β
DA Lawrence - Methods in enzymology, 1991 - Elsevier
Transforming growth factor/3 (TGF-/3) has been the subject of several recent reviews, 1.2 so
here only some of its salient properties will be recalled as an anchor point for this chapter,
which is specifically concerned with latent TGF-/3 (L-TGF-/3). In its active form TGF-/3 is
multifunctional and can stimulate or inhibit cell proliferation, cell differentiation, and cellular
function depending on cell type (eg, fibroblast or epithelial cell) and on what other growth
factors are present in the local environment. Most of our knowledge about the biological …
here only some of its salient properties will be recalled as an anchor point for this chapter,
which is specifically concerned with latent TGF-/3 (L-TGF-/3). In its active form TGF-/3 is
multifunctional and can stimulate or inhibit cell proliferation, cell differentiation, and cellular
function depending on cell type (eg, fibroblast or epithelial cell) and on what other growth
factors are present in the local environment. Most of our knowledge about the biological …