IL-9 and its receptor in allergic and nonallergic lung disease: increased expression in asthma
A Shimbara, P Christodoulopoulos… - Journal of Allergy and …, 2000 - Elsevier
Background: Bronchial asthma is a chronic inflammatory disease associated with genetic
components. Recently IL-9 has been reported as a candidate gene for asthma and to be
associated with bronchial hyperresponsiveness and elevated levels of total serum IgE.
Objective: To investigate the contribution of IL-9 to the pathogenesis of asthma, we
examined the expression of IL-9 and its receptor (IL-9R) in bronchial tissue from subjects
with atopic asthma (n= 10), chronic bronchitis (n= 11), and sarcoidosis (n= 9) and from …
components. Recently IL-9 has been reported as a candidate gene for asthma and to be
associated with bronchial hyperresponsiveness and elevated levels of total serum IgE.
Objective: To investigate the contribution of IL-9 to the pathogenesis of asthma, we
examined the expression of IL-9 and its receptor (IL-9R) in bronchial tissue from subjects
with atopic asthma (n= 10), chronic bronchitis (n= 11), and sarcoidosis (n= 9) and from …