Multiple antibiotic resistance in a bacterium with suppressed autolytic system

A Tomasz, A Albino, EVE Zanati - Nature, 1970 - nature.com
A Tomasz, A Albino, EVE Zanati
Nature, 1970nature.com
Suppressed Autolytic System Page 1 | 38 NATURE VOL. 227 JULY 1 || 1 97O Multiple
Antibiotic Resistance in a Bacterium with Suppressed Autolytic System by LLLGGGLLLL
GGGGGGLS LGGGGG LLLLLGS EVE ZANAT| The Rockefeller University, New York, 1002l
CERTAIN antibiotics can cause physical disintegration or “lysis” of cells when added to growing
cultures of sensitive bacteria". A common feature of the action of these antibiotics is that they all
interfere selectively with some step in the biosynthesis or normal assembly of bacterial cell …
Abstract
Suppression of the activity of the cellular autolytic system of pneumococci causes simultaneous resistance against penicillin, D-cycloserine and phosphonomycin. This phenomenon represents a novel type of drug resistance mechanism in bacteria.
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