Increased levels of basic fibroblast growth factor are found in the cross-clamped heart during cardiopulmonary bypass.
D Abramov, E Erez, O Dagan, Y Abramov… - … Canadian Journal of …, 2000 - europepmc.org
D Abramov, E Erez, O Dagan, Y Abramov, E Pearl, G Veena, J Katz, BA Vidne, V Barak
The Canadian Journal of Cardiology, 2000•europepmc.orgBackground High concentrations of fibroblast growth factors (FGFs) are found in the heart.
Even higher levels are measured during ischemia. Exogenous administration of FGF to
ischemic myocardium promotes synthesis of collateral coronary circulation and induces
local myocardial hypertrophy. The kinetics and the contribution of the heart and lungs to
circulating basic FGF (bFGF) levels during cardiac surgery were characterized.
Even higher levels are measured during ischemia. Exogenous administration of FGF to
ischemic myocardium promotes synthesis of collateral coronary circulation and induces
local myocardial hypertrophy. The kinetics and the contribution of the heart and lungs to
circulating basic FGF (bFGF) levels during cardiac surgery were characterized.
Background
High concentrations of fibroblast growth factors (FGFs) are found in the heart. Even higher levels are measured during ischemia. Exogenous administration of FGF to ischemic myocardium promotes synthesis of collateral coronary circulation and induces local myocardial hypertrophy. The kinetics and the contribution of the heart and lungs to circulating basic FGF (bFGF) levels during cardiac surgery were characterized.
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