Smooth muscle cell apoptosis in arteriosclerosis

M Mayr, Q Xu - Experimental gerontology, 2001 - Elsevier
Arteriosclerosis, a paradigmatic age-related disease, encompasses (spontaneous)
atherosclerosis, restenosis after percutaneous transluminal coronary angioplasty,
autologous arterial or vein graft arteriosclerosis and transplant arteriosclerosis. In all types of
arteriosclerosis, vascular smooth muscle cell (SMC) accumulation in the intima is a key
event, but abundant evidence also indicates the importance of SMC apoptosis in the
development of arteriosclerosis. Because SMC proliferation and apoptosis coincide in …