[HTML][HTML] An immortalized rat liver stellate cell line (HSC-T6): a new cell model for the study of retinoid metabolism in vitro

S Vogel, R Piantedosi, J Frank, A Lalazar… - Journal of lipid …, 2000 - ASBMB
Hepatocytes and hepatic stellate cells play important roles in retinoid storage and
metabolism. Hepatocytes process postprandial retinyl esters and are responsible for
secretion of retinol bound to retinol-binding protein (RBP) to maintain plasma retinol levels.
Stellate cells are the body's major cellular storage sites for retinoid. We have characterized
and utilized an immortalized rat stellate cell line, HSC-T6 cells, to facilitate study of the
cellular aspects of hepatic retinoid processing. For comparison, we also carried out parallel …