[PDF][PDF] T-cell differentiation: Commitment factors for T helper cells

A O'Garra - Current Biology, 2000 - cell.com
A O'Garra
Current Biology, 2000cell.com
Cytokines are dominant factors in driving the development of T helper cell subsets via
specific signaling pathways. Transcription factors specific to the T helper cell lineages have
also been shown to determine the commitment of Th1 and Th2 cells to the production of
distinct profiles of cytokines.
Abstract
Cytokines are dominant factors in driving the development of T helper cell subsets via specific signaling pathways. Transcription factors specific to the T helper cell lineages have also been shown to determine the commitment of Th1 and Th2 cells to the production of distinct profiles of cytokines.
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