Increased prebeta-HDL levels, cholesterol efflux, and LCAT-mediated esterification in mice expressing the human cholesteryl ester transfer protein (CETP) and human …
OL Francone, L Royer, M Haghpassand - Journal of lipid research, 1996 - ASBMB
The effects of cholesteryl ester transfer protein (CETP) on the distribution of apolipoprotein
(apo) AI between high density lipoprotein (HDL) subspecies and its impact on efflux and
esterification of cell-derived cholesterol was studied in transgenic mice expressing either the
human apoA-I (HuAITg) or both the human apoA-I and CETP (HuAICETPTg) transgenes.
The simultaneous expression of the human CETP and apoA-I transgenes induced a 2-fold
increase in the proportion of human apoA-I in the prebeta-HDL fraction and 1.4-and 2.2-fold …
(apo) AI between high density lipoprotein (HDL) subspecies and its impact on efflux and
esterification of cell-derived cholesterol was studied in transgenic mice expressing either the
human apoA-I (HuAITg) or both the human apoA-I and CETP (HuAICETPTg) transgenes.
The simultaneous expression of the human CETP and apoA-I transgenes induced a 2-fold
increase in the proportion of human apoA-I in the prebeta-HDL fraction and 1.4-and 2.2-fold …