Transplantation of retinal pigment epithelial cells to immature and adult rat hosts: short-and long-term survival characteristics
L Li, JE Turner - Experimental eye research, 1988 - Elsevier
Retinal pigment epithelial (RPE) cells isolated from 6–8-day-old pigmented Long-Evans rat
eyes were successfully grafted onto Bruch's membrane in albino Sprague-Dawley hosts
ranging in age from 10 days postnatal to young adulthood. Injections of RPE cells were
made into the subretinal space using a lesion paradigm which penetrates through the dorsal
surface of the eye cutting through the sclera and choroid. Suspensions of pigmented RPE
cells were labeled with Nuclear Yellow prior to transplantation, and at 1 week after grafting …
eyes were successfully grafted onto Bruch's membrane in albino Sprague-Dawley hosts
ranging in age from 10 days postnatal to young adulthood. Injections of RPE cells were
made into the subretinal space using a lesion paradigm which penetrates through the dorsal
surface of the eye cutting through the sclera and choroid. Suspensions of pigmented RPE
cells were labeled with Nuclear Yellow prior to transplantation, and at 1 week after grafting …