Lichen planus pemphigoides: identification of 180 kd hemidesmosome antigen
Y Tamada, K Yokochi, Y Nitta, T Ikeya, K Hara… - Journal of the American …, 1995 - Elsevier
We describe a man with lichen planus pemphigoides. Direct immunofluorescence studies of
peribullous skin showed linear deposition of IgG and C3 in the basement membrane zone.
Indirect immunofluorescence studies disclosed circulating anti-basement membrane zone
antibodies. Immunoelectron microscopy demonstrated binding of antibodies to the
hemidesmosomes and lamina lucida. The patient's serum defined only the minor bullous
pemphigoid antigen with a molecular weight of 180 kd. These findings suggest the …
peribullous skin showed linear deposition of IgG and C3 in the basement membrane zone.
Indirect immunofluorescence studies disclosed circulating anti-basement membrane zone
antibodies. Immunoelectron microscopy demonstrated binding of antibodies to the
hemidesmosomes and lamina lucida. The patient's serum defined only the minor bullous
pemphigoid antigen with a molecular weight of 180 kd. These findings suggest the …