[HTML][HTML] Immune clearance of phosphatidylserine-expressing cells by phagocytes: the role of β2-glycoprotein i in macrophage recognition
K Balasubramanian, J Chandra, AJ Schroit - Journal of Biological …, 1997 - ASBMB
The function of β 2-glycoprotein I (β 2 GPI), a 50-kDa serum glycoprotein, is not completely
understood but has been suggested to be involved in the regulation of thrombosis (Brighton,
TA, Hogg, PJ, Dai, Y.-P., Murray, BH, Choing, BH, and Chesterman, CN (1996) Br. J.
Haematol. 93, 185–194) and the clearance of phosphatidylserine (PS)-expressing cells
(Chonn, A., Semple SC, and Cullis PR (1995) J. Biol. Chem. 270, 25845–25849). To further
understand the role of this protein, we characterized the ability of β 2 GPI to interact with PS …
understood but has been suggested to be involved in the regulation of thrombosis (Brighton,
TA, Hogg, PJ, Dai, Y.-P., Murray, BH, Choing, BH, and Chesterman, CN (1996) Br. J.
Haematol. 93, 185–194) and the clearance of phosphatidylserine (PS)-expressing cells
(Chonn, A., Semple SC, and Cullis PR (1995) J. Biol. Chem. 270, 25845–25849). To further
understand the role of this protein, we characterized the ability of β 2 GPI to interact with PS …