[CITATION][C] Partial resolution of the enzymes catalyzing oxidative phosphorylation: X. Correlation of morphology and function in submitochondrial particles

Y Kagawa, E Racker - Journal of Biological Chemistry, 1966 - ASBMB
1. Evidence has been presented in this paper which greatly strengthens the suggestion that
the spherical particles lining the inner membranes of mitochondria are the morphological
representations of coupling factor 1 (ATPase). 2. With tritum-labeled ATPase it was shown
that treatment of reconstituted particles with 2 m urea leads to a release of radioactivity
which corresponded to the disappearance of the inner membrane spheres. 3. Certain salts,
eg KI or KSCN were shown to facilitate the cold inactivation of ATPase in mitochondrial …