Cloning and functional characterization of a rat urea transporter: expression in the brain
C Couriaud, P Ripoche, G Rousselet - Biochimica et Biophysica Acta (BBA) …, 1996 - Elsevier
A cDNA coding for a rat urea transporter is described. The 1242 bp open reading frame
codes for a 414 amino acids protein with 77.0% and 60.7% identity with the human UT11
and the rat UT2, respectively. When expressed in Xenopus oocytes, the protein induces a 10-
fold rise in urea permeability, inhibited by mercurial reagents and phloretin. The rUT11
mRNA is massively expressed in the brain.
codes for a 414 amino acids protein with 77.0% and 60.7% identity with the human UT11
and the rat UT2, respectively. When expressed in Xenopus oocytes, the protein induces a 10-
fold rise in urea permeability, inhibited by mercurial reagents and phloretin. The rUT11
mRNA is massively expressed in the brain.