[HTML][HTML] Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7

R Yoshida, T Imai, K Hieshima, J Kusuda… - Journal of Biological …, 1997 - ASBMB
By searching the expressedsequence tag (EST) data base, we identified partial cDNA
sequences encoding a novel human CC chemokine. We determined the complete cDNA
sequence that encodes a highly basic polypeptide of a total 98 amino acids with 20 to 30%
identity to other human CC chemokines. We termed this novel chemokine fromEBI1-Ligand
Chemokine as ELC (see below). The ELC mRNA was most strongly expressed in the
thymus and lymph nodes. Recombinant ELC protein was expressed as a fusion protein with …