Autoantibodies in male homosexuals and HIV infection

S Argov, A Schattner, R Burstein, ZT Handzel… - Immunology letters, 1991 - Elsevier
We have used ELISA to study the frequency of autoantibodies to several antigens in the
serum of 17 male homosexuals (MHS) negative for HIV (HIV−), 11 asymptomatic HIV
seropositive MHS (HIV+) and patients with ARC (N= 15) or AIDS (N= 13), and compared
them to 20 matched healthy heterosexual controls. Serum antibody binding to histones,
cardiolipin, ss-A, ss-B and Sm was found to be significantly higher in each of the MHS
groups studied as compared to controls (P< 0.001), and was also increased in the HIV+ …