[HTML][HTML] Molecular Cloning of Mouse Tissue Inhibitor of Metalloproteinases-3 and Its Promoter: Specific Lack of Expression in Neoplastic JB6 Cells May Reflect Altered …
Y Sun, G Hegamyer, H Kim, K Sithanandam… - Journal of Biological …, 1995 - ASBMB
Mouse tissue inhibitor of metalloproteinases-3 (mTIMP-3), a gene specifically not expressed
in neoplastic JB6 cells, has been isolated recently through the use of the mRNA differential
display technique (Sun, Y., Hegamyer, G., and Colburn, NH (1994) Cancer Res. 54, 1139-
1144). We report here the full-length mTIMP-3 cDNA sequence, the promoter sequence and
partial characterization, expression and induction of TIMP-3, and the possible molecular
basis for the lack of mTIMP-3 expression in neoplastic JB6 cells. There are three transcripts …
in neoplastic JB6 cells, has been isolated recently through the use of the mRNA differential
display technique (Sun, Y., Hegamyer, G., and Colburn, NH (1994) Cancer Res. 54, 1139-
1144). We report here the full-length mTIMP-3 cDNA sequence, the promoter sequence and
partial characterization, expression and induction of TIMP-3, and the possible molecular
basis for the lack of mTIMP-3 expression in neoplastic JB6 cells. There are three transcripts …