HPV in situ hybridization with catalyzed signal amplification and polymerase chain reaction in establishing cerebellar metastasis of a cervical carcinoma

CC Huang, ML Kashima, H Chen, IM Shih, RJ Kurman… - Human pathology, 1999 - Elsevier
We report an unusual case of cerebellar metastasis from a cervical adenosquamous
carcinoma in which molecular techniques assisted in establishing the correct diagnosis. The
patient was a 43-year-old woman with surgically unresectable cervical carcinoma
diagnosed 2 years before presenting with neurological symptoms. A magnetic resonance
imaging scan showed a large, enhancing cerebellar lesion with significant brain stem
compression. The excised cerebellar tumor resembled a small cell carcinoma and was …