[HTML][HTML] Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans
M Veugelers, B De Cat, H Ceulemans… - Journal of Biological …, 1999 - ASBMB
The glypicans compose a family of glycosylphosphatidylinositol-anchored heparan sulfate
proteoglycans. Mutations in dally, a gene encoding a Drosophila glypican, and in GPC3, the
gene for human glypican-3, implicate glypicans in the control of cell growth and division. So
far, five members of the glypican family have been identified in vertebrates. By sequencing
expressed sequence tag clones and products of rapid amplifications of cDNA ends, we
identified a sixth member of the glypican family. The glypican-6 mRNA encodes a protein of …
proteoglycans. Mutations in dally, a gene encoding a Drosophila glypican, and in GPC3, the
gene for human glypican-3, implicate glypicans in the control of cell growth and division. So
far, five members of the glypican family have been identified in vertebrates. By sequencing
expressed sequence tag clones and products of rapid amplifications of cDNA ends, we
identified a sixth member of the glypican family. The glypican-6 mRNA encodes a protein of …
