Prostaglandin and tumor necrosis factor levels in early wound inflammatory fluid: effects of parenteral omega-3 and omega-6 fatty acid administration
DN Linz, VF Garcia, G Arya, MM Ziegler - Journal of pediatric surgery, 1994 - Elsevier
Monokines are important mediators of wound healing. Specifically, the proportions of
proinflammatory (tumor necrosis factor and PGE 2) and antiinflammatory (PGF 2α)
monokines may modulate its early phases. Using a polyvinyl alcohol sponge model of rat
wounding, the authors determined the temporal changes in the levels of monokines in
wound inflammatory fluid, and examined whether dietary manipulation for 6 days with the
precursors (ω6 fatty acids) and inhibitors (fish oil ω3 fatty acids) of the prostaglandin-2 series …
proinflammatory (tumor necrosis factor and PGE 2) and antiinflammatory (PGF 2α)
monokines may modulate its early phases. Using a polyvinyl alcohol sponge model of rat
wounding, the authors determined the temporal changes in the levels of monokines in
wound inflammatory fluid, and examined whether dietary manipulation for 6 days with the
precursors (ω6 fatty acids) and inhibitors (fish oil ω3 fatty acids) of the prostaglandin-2 series …