[HTML][HTML] Characterization of the D-glucuronyl C5-epimerase involved in the biosynthesis of heparin and heparan sulfate
JP Li, F Gong, K El Darwish, M Jalkanen… - Journal of Biological …, 2001 - ASBMB
The murine gene for the glucuronyl C5-epimerase involved in heparan sulfate biosynthesis
was cloned, using a previously isolated bovine lung cDNA fragment (Li, J.-P., Hagner-
McWhirter, Å., Kjellén, L., Palgi, J., Jalkanen, M., and Lindahl, U.(1997) J. Biol. Chem. 272,
28158–28163) as probe. The∼ 11-kilobase pair mouse gene contains 3 exons from the first
ATG to stop codon and is localized to chromosome 9. Southern analysis of the genomic
DNA and chromosome mapping suggested the occurrence of a single epimerase gene …
was cloned, using a previously isolated bovine lung cDNA fragment (Li, J.-P., Hagner-
McWhirter, Å., Kjellén, L., Palgi, J., Jalkanen, M., and Lindahl, U.(1997) J. Biol. Chem. 272,
28158–28163) as probe. The∼ 11-kilobase pair mouse gene contains 3 exons from the first
ATG to stop codon and is localized to chromosome 9. Southern analysis of the genomic
DNA and chromosome mapping suggested the occurrence of a single epimerase gene …