[HTML][HTML] Collagen XVIII is a basement membrane heparan sulfate proteoglycan
W Halfter, S Dong, B Schurer, GJ Cole - Journal of Biological Chemistry, 1998 - ASBMB
The present study shows that collagen XVIII is, next to perlecan and agrin, the third basal
lamina heparan sulfate proteoglycan (HSPG) and the first collagen/proteoglycan with
heparan sulfate side chains. By using monoclonal antibodies to an unidentified HSPG in
chick, 14 cDNA clones were isolated from a chick yolk sac library. All clones had a common
nucleotide sequence that was homologous to the mRNA sequences of mouse and human
collagen XVIII. The deduced amino acid sequence of the chick fragment shows an 83 …
lamina heparan sulfate proteoglycan (HSPG) and the first collagen/proteoglycan with
heparan sulfate side chains. By using monoclonal antibodies to an unidentified HSPG in
chick, 14 cDNA clones were isolated from a chick yolk sac library. All clones had a common
nucleotide sequence that was homologous to the mRNA sequences of mouse and human
collagen XVIII. The deduced amino acid sequence of the chick fragment shows an 83 …