A preliminary study of the response to various immunotherapy models in a spontaneous
murine al cell carcinoma model is reported. Tumor cells were implanted intrarenally and
nephrectomy performed at a later time. Specific immunotherapy using irradiated whole
tumor cells plus complete Freund's adjuvant and a crude membrane preparation plus the
same adjuvant were compared to nonspecific immunotherapy with adjuvant alone. In the 1st
of 2 response criteria examined, there was a statistically significant decrease in tumor …