Publisher Summary Although interleukin-12 (IL-12) has been discovered only relatively
recently, a remarkable level of knowledge has been obtained for this cytokine, and many
possible therapeutic applications are being tested or have been proposed. It performs the
dual function as a proinflammatory cytokine and as an immunomodulatory molecule. This
chapter describes the structure, genetics, induction, and biological functions of IL-12. Being
produced at the early times of inflammation in response to infection or other stimuli, IL-12 …