[HTML][HTML] Purification and Characterization of a Novel Stress Protein, the 150-kDa Oxygen-regulated Protein (ORP150), from Cultured Rat Astrocytes and Its Expression …

K Kuwabara, M Matsumoto, J Ikeda, O Hori… - Journal of Biological …, 1996 - ASBMB
As the most abundant cell type in the central nervous system, astrocytes are positioned to
nurture and sustain neurons, especially in response to cellular stresses, which occur in
ischemic cerebrovascular disease. In a previous study (Hori, O., Matsumoto, M., Kuwabara,
K., Maeda, M., Ueda, H., Ohtsuki, T., Kinoshita, T., Ogawa, S., Kamada, T., and Stern,
D.(1996) J. Neurochem., in press), we identified five polypeptide bands on SDS-
polyacrylamide gel electrophoresis, corresponding to molecular masses of about 28, 33, 78 …