[HTML][HTML] Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells (∗)
Vascular endothelial growth factor (VEGF) is an endothelial specific angiogenic mitogen
secreted from various cell types including tumor cells. Increasing evidence suggests that
VEGF is a major regulator of physiological and pathological angiogenesis, and the
VEGF/VEGF receptor system has been shown to be necessary for glioma angiogenesis.
Hypoxia seems to play a critical role in the induction of VEGF expression during glioma
progression. C6 glioma cells provide an in vivo glioma model for the study of tumor …
secreted from various cell types including tumor cells. Increasing evidence suggests that
VEGF is a major regulator of physiological and pathological angiogenesis, and the
VEGF/VEGF receptor system has been shown to be necessary for glioma angiogenesis.
Hypoxia seems to play a critical role in the induction of VEGF expression during glioma
progression. C6 glioma cells provide an in vivo glioma model for the study of tumor …