Cloning and sequencing of a human cDNA encoding endothelial P2Y1 purinoceptor
C Léon, C Vial, JP Cazenave, C Gachet - Gene, 1996 - Elsevier
C Léon, C Vial, JP Cazenave, C Gachet
Gene, 1996•ElsevierWe have cloned and sequenced a 3055-bp human placenta cDNA encoding a P2
purinoceptor. An identical receptor has also been found in human saphenous vein
endothelial cells. Comparison of the deduced amino acid (aa) sequence to those of
previously described P2Y1 purinoceptors revealed greater than 95% aa identity with the rat
and mouse counterparts, and 83% with the chick P2Y1 purinoceptor. Northern blot
experiments revealed two mRNAs of 7.5 and 4.6 kb whose expression varies according to …
purinoceptor. An identical receptor has also been found in human saphenous vein
endothelial cells. Comparison of the deduced amino acid (aa) sequence to those of
previously described P2Y1 purinoceptors revealed greater than 95% aa identity with the rat
and mouse counterparts, and 83% with the chick P2Y1 purinoceptor. Northern blot
experiments revealed two mRNAs of 7.5 and 4.6 kb whose expression varies according to …
We have cloned and sequenced a 3055-bp human placenta cDNA encoding a P2 purinoceptor. An identical receptor has also been found in human saphenous vein endothelial cells. Comparison of the deduced amino acid (aa) sequence to those of previously described P2Y1 purinoceptors revealed greater than 95% aa identity with the rat and mouse counterparts, and 83% with the chick P2Y1 purinoceptor. Northern blot experiments revealed two mRNAs of 7.5 and 4.6 kb whose expression varies according to the tissue examined.
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