Distribution and function of prostanoid receptors: studies from knockout mice

Y Sugimoto, S Narumiya, A Ichikawa - Progress in lipid research, 2000 - Elsevier
Recent developments in the molecular biology of the prostanoid receptors has allowed the
investigation of the physiological roles of each individual receptor type and subtype. The
following article reports the prostanoid receptor distributions deduced from Northern blot and
in situ hybridization analyses, summarizes the phenotypes of each receptor knockout mice,
and discusses recent studies investigating the effects of each receptor deficiency on the
inflammatory response and female reproductive processes. The combination of expression …