Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

J Selhub, PF Jacques, PWF Wilson, D Rush… - Jama, 1993 - jamanetwork.com
Objective.—To describe the distribution of plasma homocysteine concentrations in an
elderly population and to analyze the relationship between homocysteine level and intake of
vitamins and serum levels of vitamins that serve as coenzymes in homocysteine metabolism.
Design.—Cross-sectional analysis of homocysteine levels and vitamin blood levels and
intake in elderly participants in the Framingham Study. Setting.—Population-based cohort in
Framingham, Mass. Participants.—A total of 1160 adult survivors, aged 67 to 96 years, from …