Hypoxic neuropathy Does hypoxia play a role in diabetic neuropathy? The 1988 Robert Wartenberg lecture
PJ Dyck - Neurology, 1989 - AAN Enterprises
PJ Dyck
Neurology, 1989•AAN EnterprisesIn this report I review:(1) the blood supply and endoneurial microenvironment of nerve;(2)
the class, type, and spatial distribution of nerve fiber degeneration as a function of number,
site, and class of vessels occluded;(3) the putative mechanisms of nerve hypoxia; and (4)
the role of hypoxia in diabetic polyneuropathy.
the class, type, and spatial distribution of nerve fiber degeneration as a function of number,
site, and class of vessels occluded;(3) the putative mechanisms of nerve hypoxia; and (4)
the role of hypoxia in diabetic polyneuropathy.
In this report I review: (1) the blood supply and endoneurial microenvironment of nerve; (2) the class, type, and spatial distribution of nerve fiber degeneration as a function of number, site, and class of vessels occluded; (3) the putative mechanisms of nerve hypoxia; and (4) the role of hypoxia in diabetic polyneuropathy.
American Academy of Neurology