[HTML][HTML] Oxidation-reduction properties of methylglyoxal-modified protein in relation to free radical generation
C Lee, MB Yim, PB Chock, HS Yim, SO Kang - Journal of biological …, 1998 - ASBMB
Oxidation-reduction properties of methylglyoxal-modified protein in relation to free radical
generation were investigated. Glycation of bovine serum albumin by methylglyoxal
generated the protein-bound free radical, probably the cation radical of the cross-linked
Schiff base, as observed in the reaction of methylglyoxal with l-alanine (Yim, H.-S., Kang, S.-
O., Hah, YC, Chock, PB, and Yim, MB (1995) J. Biol. Chem. 270, 28228–28233) or withN α-
acetyl-l-lysine. The glycated bovine serum albumin showed increased electrophoretic …
generation were investigated. Glycation of bovine serum albumin by methylglyoxal
generated the protein-bound free radical, probably the cation radical of the cross-linked
Schiff base, as observed in the reaction of methylglyoxal with l-alanine (Yim, H.-S., Kang, S.-
O., Hah, YC, Chock, PB, and Yim, MB (1995) J. Biol. Chem. 270, 28228–28233) or withN α-
acetyl-l-lysine. The glycated bovine serum albumin showed increased electrophoretic …