Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2
SL Swendeman, C Spielholz, NA Jenkins… - Journal of Biological …, 1994 - ASBMB
We recently cloned murine and human cDNAs that encode CP2, a cellular transcription
factor that interacts with the alpha-globin promoter as well as with additional cellular and
viral promoter elements. We have now characterized the genomic structure, chromosome
location, promoter, and expression pattern of the factor. Genes for the murine and human
mRNAs contained 16 and 15 exons, respectively. Both genes spanned approximately 30
kilobases of chromosomal DNA, and among coding exons, all exon/intron boundaries were …
factor that interacts with the alpha-globin promoter as well as with additional cellular and
viral promoter elements. We have now characterized the genomic structure, chromosome
location, promoter, and expression pattern of the factor. Genes for the murine and human
mRNAs contained 16 and 15 exons, respectively. Both genes spanned approximately 30
kilobases of chromosomal DNA, and among coding exons, all exon/intron boundaries were …