Ion channels and exchangers that mediate ischemic neuronal injury

JJ Vornov - Current opinion in neurology, 1998 - journals.lww.com
Current opinion in neurology, 1998journals.lww.com
Preventing the loss of ion homeostasis or promoting its recovery are two primary targets of
neuroprotective strategies. The contribution of excitatory neurotransmitter receptor linked ion
channels is now well established. Sodium and calcium may also enter neurons and glia
through voltage sensitive channels and exchangers, contributing directly and indirectly to
injury. Curr Opin Neurol 11: 39–43.© 1998 Rapid Science Ltd
Abstract
Preventing the loss of ion homeostasis or promoting its recovery are two primary targets of neuroprotective strategies. The contribution of excitatory neurotransmitter receptor linked ion channels is now well established. Sodium and calcium may also enter neurons and glia through voltage sensitive channels and exchangers, contributing directly and indirectly to injury. Curr Opin Neurol 11: 39–43.© 1998 Rapid Science Ltd
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