[PDF][PDF] New diagnostic criteria for multiple sclerosis: guidelines for research protocols

CM Poser, DW Paty, L Scheinberg… - Annals of Neurology …, 1983 - testyprelekarov.sk
CM Poser, DW Paty, L Scheinberg, WI McDonald, FA Davis, GC Ebers, KP Johnson…
Annals of Neurology: Official Journal of the American Neurological …, 1983testyprelekarov.sk
Several schemes for the diagnosis and clinical classification of multiple sclerosis (MS) have
been advanced [l}. The best known is that published by Schumacher et alC31. The criteria
for this scheme were established in order to select patients for participation in therapeutic
trials, and pertain only to what might be called definite MS. No provision was made for
incorporating supportive laboratory data into the diagnostic criteria. As no reliable specific
laboratory test for the diagnosis of MS has been discovered, the diagnosis remains a clinical …
Several schemes for the diagnosis and clinical classification of multiple sclerosis (MS) have been advanced [l}. The best known is that published by Schumacher et alC31. The criteria for this scheme were established in order to select patients for participation in therapeutic trials, and pertain only to what might be called definite MS. No provision was made for incorporating supportive laboratory data into the diagnostic criteria.
As no reliable specific laboratory test for the diagnosis of MS has been discovered, the diagnosis remains a clinical one, and there is still a need for clinical diagnostic criteria. However, several laboratory and clinical procedures have been developed within the last decade which aid greatly in demonstrating neurological dysfunction attributable to lesions, and even the lesions themselves.
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