Relationship between cAMP and Ca2+ fluxes in human platelet membranes
J Enouf, R Bredoux, N Bourdeau, F Giraud, C Le Peuch… - Biochimie, 1987 - Elsevier
The effect of cAMP (which involved a 23 kDa protein phosphorylation) has been studied on
the Ca 2+ uptake and Ca 2+ release from a human platelet membrane vesicle fraction. It
was tested in the presence of the catalytic subunit of the cAMP-dependent protein kinase (C
Sub). The addition of C Sub increased the steady state level of the Ca 2+ uptake into the
membrane vesicles. The effect was enhanced when tested in the absence of Ca 2+
precipitating agent. The response was proportional to the dose of C Sub. Moreover, the …
the Ca 2+ uptake and Ca 2+ release from a human platelet membrane vesicle fraction. It
was tested in the presence of the catalytic subunit of the cAMP-dependent protein kinase (C
Sub). The addition of C Sub increased the steady state level of the Ca 2+ uptake into the
membrane vesicles. The effect was enhanced when tested in the absence of Ca 2+
precipitating agent. The response was proportional to the dose of C Sub. Moreover, the …