Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells?

CA Lee - Trends in microbiology, 1997 - cell.com
CA Lee
Trends in microbiology, 1997cell.com
Type III secretion systems in certain bacterial pathogens are induced upon contact with host
cells and directly deliver virulence proteins into the host cell cytosol. The increasing number
of Gram-negative bacterial pathogens discovered to encode type III secretion systems raises
interesting questions. Are type III systems generic machines that deliver virulence proteins
into host cells? Is contact with host cells a common regulatory cue for type III systems?
Type III secretion systems in certain bacterial pathogens are induced upon contact with host cells and directly deliver virulence proteins into the host cell cytosol. The increasing number of Gram-negative bacterial pathogens discovered to encode type III secretion systems raises interesting questions. Are type III systems generic machines that deliver virulence proteins into host cells? Is contact with host cells a common regulatory cue for type III systems?
cell.com