Surfactant proteins A (SP-A) and D (SP-D): levels in human amniotic fluid and localization in the fetal membranes
K Miyamura, R Malhotra, HJ Hoppe, KBM Reid… - … et Biophysica Acta (BBA …, 1994 - Elsevier
Abstract Surfactant proteins A (SP-A) and D (SP-D) are major proteins, in the lung, which are
composed of collagenous and globular domains. They show an overall similarity to the
serum complement protein C1q, which is involved in the initiation of antibody-dependent
defence mechanisms. Both SP-A and SP-D were detected, immunochemically, in amniotic
fluid as early as 26 weeks gestation and, as expected, SP-A levels rose sharply from 32
weeks towards term. By contrast, SP-D levels in the same samples rose only moderately …
composed of collagenous and globular domains. They show an overall similarity to the
serum complement protein C1q, which is involved in the initiation of antibody-dependent
defence mechanisms. Both SP-A and SP-D were detected, immunochemically, in amniotic
fluid as early as 26 weeks gestation and, as expected, SP-A levels rose sharply from 32
weeks towards term. By contrast, SP-D levels in the same samples rose only moderately …