Publisher Summary Myeloperoxidase (donor: hydrogen-peroxide oxidoreductase) is the
most abundant protein in neutrophils and is also found in monocytes. It contains two heme-
prosthetic groups and is a unique peroxidase that catalyzes the conversion of hydrogen
peroxide and chloride to hypochlorous acid. Hydrogen peroxide is formed from the
spontaneous dismutation of superoxide, which is produced by an NADPH oxidase in the cell
membrane. Hypochlorous acid is the major strong oxidant produced by neutrophils. It has …