Neuropeptide Y (NPY)-induced feeding behavior in female rats: comparison with human NPY ([Met17] NPY), NPY analog ([norLeu4] NPY) and peptide YY
JT Clark, A Sahu, PS Kalra, A Balasubramaniam… - Regulatory peptides, 1987 - Elsevier
Porcine neuropeptide Y (pNPY) administered into the third ventricle of the brain is known to
elicit a powerful feeding response in steroid-treated ovariectomized and intact male rats. The
present study compared the effects of pNPY and 3 structurally related peptides, human NPY
(hNPY), an analog of NPY (NPY-A,[norLeu4] NPY) and peptide YY (PYY) on feeding
behavior in intact female rats. Intraventricular administration of pNPY, hNPY, NPY-A and
PYY over a dose range of 0.5 to 10 μg evoked feeding behavior to a varying extent …
elicit a powerful feeding response in steroid-treated ovariectomized and intact male rats. The
present study compared the effects of pNPY and 3 structurally related peptides, human NPY
(hNPY), an analog of NPY (NPY-A,[norLeu4] NPY) and peptide YY (PYY) on feeding
behavior in intact female rats. Intraventricular administration of pNPY, hNPY, NPY-A and
PYY over a dose range of 0.5 to 10 μg evoked feeding behavior to a varying extent …