[HTML][HTML] The role of syndecan cytoplasmic domain in basic fibroblast growth factor-dependent signal transduction

R Volk, JJ Schwartz, J Li, RD Rosenberg… - Journal of Biological …, 1999 - ASBMB
To determine the role played by syndecan-4 cytoplasmic domain in the mediation of basic
fibroblast growth factor (bFGF) signaling, immortalized human cells (ECV) were used to
generate cell lines expressing constructs encoding full-length sequences for syndecan-4
(S4), syndecan-1 (S1), glypican-1 (G1), or chimeric proteins consisting of the ectoplasmic
domain of glypican-1 linked to the transmembrane/cytoplasmic domain of syndecan-4 (G1-
S4c) and the ectoplasmic domain of syndecan-4 linked to the glypican-1 …