Lipoprotein abnormalities associated with lipopolysaccharide-induced lecithin: cholesterol acyltransferase and lipase deficiency
BJ Auerbach, JS Parks - Journal of Biological Chemistry, 1989 - ASBMB
Density gradient ultracentrifugation was used to isolate and characterize the plasma
lipoproteins from African green monkeys before and 24 and 48 h after subcutaneous
injection of 300 µg/kg lipopolysaccharide (LPS) to induce an acute phase response.
Compared with 0 h values, reductions occurred in plasma cholesterol (39%), high density
lipoprotein (HDL) cholesterol (54%), lecithin: cholesterol acyltransferase (LCAT) activity
(55%), and post-heparin plasma lipase activity (68%) 48 h after LPS injection while plasma …
lipoproteins from African green monkeys before and 24 and 48 h after subcutaneous
injection of 300 µg/kg lipopolysaccharide (LPS) to induce an acute phase response.
Compared with 0 h values, reductions occurred in plasma cholesterol (39%), high density
lipoprotein (HDL) cholesterol (54%), lecithin: cholesterol acyltransferase (LCAT) activity
(55%), and post-heparin plasma lipase activity (68%) 48 h after LPS injection while plasma …