[HTML][HTML] Functional differences between transplantable human hematopoietic stem cells from fetal liver, cord blood, and adult marrow
TL Holyoake, FE Nicolini, CJ Eaves - Experimental hematology, 1999 - Elsevier
The purpose of this study was to develop a simple assay for quantitating transplantable
human lymphomyeloid stem cells (competitive repopulating units [CRU]) to enable
comparison among the numbers and types of progeny generated in NOD/SCID mice by
such cells from different ontologic sources. Sublethally irradiated NOD/SCID mice were
transplanted with varying numbers of CD34+ cell-enriched suspensions of human fetal liver,
cord blood, or adult marrow cells. The types and numbers of human cells present in the …
human lymphomyeloid stem cells (competitive repopulating units [CRU]) to enable
comparison among the numbers and types of progeny generated in NOD/SCID mice by
such cells from different ontologic sources. Sublethally irradiated NOD/SCID mice were
transplanted with varying numbers of CD34+ cell-enriched suspensions of human fetal liver,
cord blood, or adult marrow cells. The types and numbers of human cells present in the …