Osteoarthritis (OA) is a disease mostly characterized by biochemical, physical and
histological abnormalities of cartilage. Hence, the term osteoarthrosis has been preferred by
some clinicians in order to emphasize the lack of a primary inflammatory process in this
arthropathy. However, articular and periarticular inflammation is an early and sometimes
prominent feature of OA and is present at some point in the disease course of the majority of
patients with OA. Inflammation in OA is often unnoticed since the cardinal features of …