[PDF][PDF] Innate immunity: Lipoproteins take their Toll on the host

CA Janeway, R Medzhitov - Current Biology, 1999 - cell.com
CA Janeway, R Medzhitov
Current Biology, 1999cell.com
Innate immunity: Lipoproteins take their Toll on the host Page 1 Dispatch R879 Innate immunity:
Lipoproteins take their Toll on the host Charles A. Janeway, Jr and Ruslan Medzhitov A family
of mammalian Toll-like receptors (TLRs) has a critical role in the recognition of microbial
infection. Recent evidence suggests that bacterial lipoproteins — major components of bacterial
cell walls — are recognized by a member of the human TLR family. Address: Yale University
School of Medicine, Section of Immunobiology, 310 Cedar Street, LH416, PO Box 208011, New …
Abstract
A family of mammalian Toll-like receptors (TLRs) has a critical role in the recognition of microbial infection. Recent evidence suggests that bacterial lipoproteins – major components of bacterial cell walls – are recognized by a member of the human TLR family.
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