Association between activation of the renin-angiotensin system and secondary erythrocytosis in patients with chronic obstructive pulmonary disease

DV Vlahakos, EN Kosmas, I Dimopoulou… - The American journal of …, 1999 - Elsevier
PURPOSE: An association between activation of the renin-angiotensin system and
enhanced erythropoiesis has been observed in patients with several diseases, including
congestive heart failure and hypertension. Our goal was to examine whether the renin-
angiotensin system is associated with secondary erythrocytosis in patients with chronic
obstructive pulmonary disease (COPD). SUBJECTS AND METHODS: Plasma renin activity,
plasma aldosterone concentration, serum erythropoietin level, and serum angiotensin …