Regulation of prolactin secretion by oestrogens: physiological and pathological significance.
S Franks - 1983 - cabidigitallibrary.org
1983•cabidigitallibrary.org
Oestrogen is one of the most important of the physiological stimuli that can override tonic
inhibitory control of prolactin (PRL) secretion by dopamine. Mechanisms of physiological
regulation of PRL secretion by oestrogens, possible importance of 2-and 4-hydroxy
oestrogens (catechol oestrogens), and role of oestrogens in pathological
hyperprolactinaemia are discussed. The emphasis is on studies in humans.
inhibitory control of prolactin (PRL) secretion by dopamine. Mechanisms of physiological
regulation of PRL secretion by oestrogens, possible importance of 2-and 4-hydroxy
oestrogens (catechol oestrogens), and role of oestrogens in pathological
hyperprolactinaemia are discussed. The emphasis is on studies in humans.
Abstract
Oestrogen is one of the most important of the physiological stimuli that can override tonic inhibitory control of prolactin (PRL) secretion by dopamine. Mechanisms of physiological regulation of PRL secretion by oestrogens, possible importance of 2- and 4-hydroxy oestrogens (catechol oestrogens), and role of oestrogens in pathological hyperprolactinaemia are discussed. The emphasis is on studies in humans.
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