Hepatitis C: the clinical spectrum of disease
JH Hoofnagle - Hepatology, 1997 - journals.lww.com
Hepatitis C virus (HCV) accounts for approximately 20% of cases of acute hepatitis, 70% of
chronic hepatitis, and 30% of end-stage liver disease in the United States. The acute
infection has an incubation period of 7 weeks (range, 4-20 weeks) and is symptomatic and
icteric in only one third of patients. Serum aminotransferase levels generally increase
greater than 10-fold elevated and as symptoms and signs resolve decrease into the normal
range. Antibody to HCV is usually but not always present at the time of onset of symptoms …
chronic hepatitis, and 30% of end-stage liver disease in the United States. The acute
infection has an incubation period of 7 weeks (range, 4-20 weeks) and is symptomatic and
icteric in only one third of patients. Serum aminotransferase levels generally increase
greater than 10-fold elevated and as symptoms and signs resolve decrease into the normal
range. Antibody to HCV is usually but not always present at the time of onset of symptoms …
Hepatitis C: a multifaceted disease: review of extrahepatic manifestations
SC Gumber, S Chopra - Annals of internal medicine, 1995 - acpjournals.org
Purpose: To review the available data on the association between hepatitis C virus (HCV)
infection and conditions reportedly related to infection with the virus and to assess the
clinical implications of these associations. Data Sources: Pertinent articles were identified
using the Paperchase database, which simultaneously searches the MEDLINE (1966 to
present), Health (1975 to present), AIDSLINE (1980 to present), and Cancerlit databases.
Study Selection: All studies for a given association were reviewed, but special attention was …
infection and conditions reportedly related to infection with the virus and to assess the
clinical implications of these associations. Data Sources: Pertinent articles were identified
using the Paperchase database, which simultaneously searches the MEDLINE (1966 to
present), Health (1975 to present), AIDSLINE (1980 to present), and Cancerlit databases.
Study Selection: All studies for a given association were reviewed, but special attention was …
Hepatitis a
RS Koff - The Lancet, 1998 - thelancet.com
Epidemiology The incubation period of hepatitis A is 15–50 days, with a mean of about 30
days. HAV is excreted in the faeces for 1–2 weeks before the onset of illness, and for at least
1 week afterwards. Viral shedding is greatest at the onset of symptoms and then declines
rapidly. Faecal excretion for several months has been reported in a few infected neonates
and adults, measured by highly sensitive techniques, 9 but the epidemiological importance
of this finding remains uncertain. HAV RNA can also be detected in blood during the …
days. HAV is excreted in the faeces for 1–2 weeks before the onset of illness, and for at least
1 week afterwards. Viral shedding is greatest at the onset of symptoms and then declines
rapidly. Faecal excretion for several months has been reported in a few infected neonates
and adults, measured by highly sensitive techniques, 9 but the epidemiological importance
of this finding remains uncertain. HAV RNA can also be detected in blood during the …
Hepatitis C virus
M Houghton, QL Choo, G Kuo - 1995 - Google Patents
IE62868B1 - Hepatitis C virus - Google Patents IE62868B1 - Hepatitis C virus - Google Patents
Hepatitis C virus Info Publication number IE62868B1 IE62868B1 IE347288A IE347288A
IE62868B1 IE 62868 B1 IE62868 B1 IE 62868B1 IE 347288 A IE347288 A IE 347288A IE
347288 A IE347288 A IE 347288A IE 62868 B1 IE62868 B1 IE 62868B1 Authority IE Ireland
Prior art keywords hcv sequence polypeptide clone cdna Prior art date 1987-11-18 Application
number IE347288A Other languages English (en) Other versions IE883472L (en Inventor …
Hepatitis C virus Info Publication number IE62868B1 IE62868B1 IE347288A IE347288A
IE62868B1 IE 62868 B1 IE62868 B1 IE 62868B1 IE 347288 A IE347288 A IE 347288A IE
347288 A IE347288 A IE 347288A IE 62868 B1 IE62868 B1 IE 62868B1 Authority IE Ireland
Prior art keywords hcv sequence polypeptide clone cdna Prior art date 1987-11-18 Application
number IE347288A Other languages English (en) Other versions IE883472L (en Inventor …