Cellular immune mechanisms in myosin-induced myocarditis
C Pummerer, G Grässl, N Neu - European heart journal, 1995 - academic.oup.com
C Pummerer, G Grässl, N Neu
European heart journal, 1995•academic.oup.comCardiac myosin-induced myocarditis proved to be a valuable virus-free murine model with
which to investigate auto-immunological mechanisms in inflammatory heart disease. The
disease was shown to be T cell-mediated. In this contribution the functional role ofCD4 and
CD8 molecules and the conditions that are required to make the cardiac tissue susceptible
to an autoimmune attack are discussed
which to investigate auto-immunological mechanisms in inflammatory heart disease. The
disease was shown to be T cell-mediated. In this contribution the functional role ofCD4 and
CD8 molecules and the conditions that are required to make the cardiac tissue susceptible
to an autoimmune attack are discussed
Abstract
Cardiac myosin-induced myocarditis proved to be a valuable virus-free murine model with which to investigate auto-immunological mechanisms in inflammatory heart disease. The disease was shown to be T cell-mediated. In this contribution the functional role ofCD4 and CD8 molecules and the conditions that are required to make the cardiac tissue susceptible to an autoimmune attack are discussed
Oxford University Press