Oral tolerance: mechanisms and therapeutic applications
AMC Faria, HL Weiner - Advances in immunology, 1999 - Elsevier
Publisher Summary This chapter discusses the mechanisms and therapeutic applications of
oral tolerance. The most striking characteristic of the gut mucosa is the abundance of the
lymphoid tissue associated with it. There are 10 12 lymphoid cells per meter of human small
intestine. Cell surface molecules and cytokines associated with inductive events in the gut
that generate and modulate oral tolerance are not completely understood. Three major
immunological consequences of oral antigen administration are described in the chapter …
oral tolerance. The most striking characteristic of the gut mucosa is the abundance of the
lymphoid tissue associated with it. There are 10 12 lymphoid cells per meter of human small
intestine. Cell surface molecules and cytokines associated with inductive events in the gut
that generate and modulate oral tolerance are not completely understood. Three major
immunological consequences of oral antigen administration are described in the chapter …