The scid Mouse Mutant

M Bosma, W Schuler, G Bosma - Genetics of Immunological Diseases, 1988 - Springer
M Bosma, W Schuler, G Bosma
Genetics of Immunological Diseases, 1988Springer
The scid mutation occurred in the CB-17Icr (CB-17) inbred strain, an immunoglobulin heavy
chain (Igh) congenic partner strain of BALB/cAnlcr (BALB/c). The CB-17 strain was derived
from the 13th backcross generation of the original CB stock of M. Potter. CB-17 mice are not
known to differ from BALB/c mice except that a portion of their chromosome 12 comes from
the C57BL/Ka strain and includes the C57BL/Ka Igh locus and other closely-linked genes.
Abstract
The scid mutation occurred in the C.B-17Icr (C.B-17) inbred strain, an immunoglobulin heavy chain (Igh) congenic partner strain of BALB/cAnlcr (BALB/c) . The C.B-17 strain was derived from the 13th backcross generation of the original C.B stock of M. Potter. C.B-17 mice are not known to differ from BALB/c mice except that a portion of their chromosome 12 comes from the C57BL/Ka strain and includes the C57BL/Ka Igh locus and other closely-linked genes.
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